Peripheral neuropathy during longterm high-dose amiodarone therapy.

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Peripheral neuropathy during longterm high-dose amiodarone therapy.

Three patients developed peripheral neuropathy after taking amiodarone for more than 18 months. All had high serum concentrations of amiodarone and its desethyl metabolite; in one patient concentrations in a sural nerve biopsy were 80 times higher than in serum. Peripheral neuropathy is a complication of large doses of amiodarone taken over long periods.

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1985

ISSN: 0022-3050

DOI: 10.1136/jnnp.48.6.576